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Zap-70 monoclonal antibody (11H40)

 
ADI-905-681-100 100 µg 291.00 USD
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Product Specification

Alternative Name:ζ-chain associated protein kinase
 
Clone:11H40
 
Host:Mouse
 
Immunogen:Recombinant full length human Zap-70.
 
UniProt ID:P43403
 
Species reactivity:Human, Rat
 
Applications:IHC (PS), WB
 
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~70kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 0.09% sodium azide and 50% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Zeta-associated protein 70 (Zap-70) is a cytoplasmic protein tyrosine required for T cell antigen receptor (TCR) signaling and development. ZAP-70 interacts with the TCR by binding to tyrosine-phosphorylated immunoreceptor tyrosine-based activation motifs (ITAMs) present in the invariant subunits of the TCR complex.
 
905-681 WB
Western blot analysis of whole cell lysate (20μg (Lane 2 = Jurkat, Lane 3 = Rat Thymus)) and recombinant human Zap-70 (GST-tagged; Lane 4) with anti-Zap-70 mAb used at 1µg/ml.
ADI-905-681 IHC1
IHC Analysis: Human thymus tissue stained with Zap-70, mAb (11H40) at 20µg/ml.
ADI-905-681 IHC2
IHC Analysis: Human tonsil tissue stained with Zap-70, mAb (11H40) at 20µg/ml.
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905-681 WB ADI-905-681 IHC1 ADI-905-681 IHC2

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