Analog to ampicillin (Prod. No. ALX-380-268). Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Effective against Gram-positive and Gram-negative bacteria and Pseudomonas.
Product Details
| Alternative Name: | α-Carboxybenzylpenicillin . 2Na |
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| Formula: | C17H16N2O6S . 2Na |
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| MW: | 376.4 . 46.0 |
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| Source: | Semisynthetic from penicillin. |
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| CAS: | 4800-94-6 |
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| MI: | 14: 1792 |
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| RTECS: | ON9105000 |
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| Purity: | ≥92% (Assay) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in water (50mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
New carbenicillin-hydrolyzing beta-lactamase (CARB-7) from Vibrio cholerae non-O1, non-O139 strains encoded by the VCR region of the V. cholerae genome: R. Melano, et al.; Antimicrob. Agents Chemother.
46, 2162 (2002),
Abstract;
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Stereoselective renal tubular secretion of carbenicillin: T. Itoh, et al.; Antimicrob. Agents Chemother.
37, 2327 (1993),
Abstract;
Full Text
Nucleotide sequence and characterization of a carbenicillin-hydrolyzing penicillinase gene from Proteus mirabilis: Y. Sakurai, et al.; J. Bacteriol.
173, 7038 (1991),
Abstract;
Full Text
In vitro susceptibility of Pseudomonas species to carbenicillin and trimethoprim-sulfamethoxazole: S.F. Hill, et al.; J. Clin. Microbiol.
22, 465 (1985),
Abstract;
Full Text
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