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Ampicillin . sodium salt

ALX-380-268-G005 5 g 67.00 USD
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β-Lactam antibiotic. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking). Inactivates transpeptidases on the inner surface of the bacterial cell membrane. Effective against Gram-negative and Gram-positive bacteria. Is inactivated by β-lactamase.

Product Details

Alternative Name:D-(-)-α-Aminobenzylpenicillin . Na
Formula:C16H18N3O4S . Na
MW:348.4 . 23.0
Source:Semisynthetic from penicillin.
MI:14: 586
Purity:≥93% (Assay)
Appearance:White to light yellow powder.
Solubility:Soluble in water (50mg/ml).
Shipping:Ambient Temperature
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

Nerve growth factor and epidermal growth factor rescue PC12 cells from programmed cell death induced by etoposide: distinct modes of protection against cell death by growth factors and a protein-synthesis inhibitor: M. Nakajima, et al.; Neurosci. Lett. 176, 161 (1994), Abstract;
Schedule-dependent effects of two consecutive, divided, low doses of actinomycin D on translocation of protein B23, inhibition of cell growth and RNA synthesis in HeLa cells: B.Y. Yung, et al.; Int. J. Cancer 52, 317 (1992), Abstract;
Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis: S.J. Martin, et al.; J. Immunol. 145, 1859 (1990), Abstract;
Short exposure to actinomycin D induces "reversible" translocation of protein B23 as well as "reversible" inhibition of cell growth and RNA synthesis in HeLa cells: B.Y. Yung, et al.; Cancer Res. 50, 5987 (1990), Abstract;
Sulbactam/ampicillin. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic use: D.M. Campoli-Richards & R.N. Brogden; Drugs 33, 577 (1987), Abstract;
N7-Substituted 7-aminoactinomycin D analogues. Synthesis and biological properties: M.S. Madhavarao, et al.; J. Med. Chem. 21, 958 (1978), Abstract;
7-substituted actinomycin D analogs. Chemical and growth-inhibitory studies: S.K. Sengupta, et al.; J. Med. Chem. 18, 1175 (1975), Abstract;

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