Most efficient spin trap for the in vitro and in vivo detection of O-, N-, S- and C-centered free radicals. Has a longer life-time than DMPO (Prod. No. ALX-430-090). Can distinguish between superoxide-dependent and independent mechanisms that lead to the hydroxyl radical. Less lipophilic (Kp=0.16) than DIPPMPO (Prod. No. ALX-430-119).
Product Details
| Alternative Name: | 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide, 2-Diethylphosphono-2-methyl-3,4-dihydro-2H-pyrrole 1-oxide, (2-Methyl-3,4-dihydro-1-oxide-2H-pyrrol-2-yl)diethylphosphonate |
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| Formula: | C9H18NO4P |
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| MW: | 235.2 |
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| CAS: | 157230-67-6 |
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| Purity: | ≥99% (TLC) |
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| Appearance: | Colorless to light yellow oil. |
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| Solubility: | Soluble in water, methylene chloride or 100% ethanol. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Unstable in solution. Reconstitute just prior to use. |
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| Handling: | Protect from light and moisture. Keep under inert gas. Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Spectrum of the (O2-)-DEPMPO adduct.
Spectrum of the (HO)-DEPMPO adduct.
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The line asymmetry of electron spin resonance spectra as a tool to determine the cis:trans ratio for spin-trapping adducts of chiral pyrrolines N-oxides: the mechanism of formation of hydroxyl radical adducts of EMPO, DEPMPO, and DIPPMPO: M. Culcasi, et al.; Free Radic. Biol. Med.
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Characterization of the high-resolution ESR spectra of superoxide radical adducts of 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide (DEPMPO) and 5,5-dimethyl-1-pyrroline N-oxide (DMPO). Analysis of conformational exchange: S. Dikalov, et al.; Free Radic. Res.
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Detection of hydrogen atom adduct of spin-trap DEPMPO. The relevance for studies of biological systems: M. Mojovic, et al.; J. Chem. Inf. Model.
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