Spin trap, useful for both in vitro and in vivo experiments.
Product Details
| Alternative Name: | 4-Oxo-2,2,6,6-tetramethylpiperidine-1-oxyl, 4-Oxo-TEMPO |
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| Formula: | C9H16NO2 |
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| MW: | 170.2 |
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| CAS: | 2896-70-0 |
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| Purity: | ≥98% (Assay) |
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| Identity: | Determined by IR. |
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| Appearance: | Orange crystalline powder. |
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| Solubility: | Soluble in acetone, DMSO, diethylether, 100% ethanol or water. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Metabolism of the stable nitroxyl radical 4-oxo-2,2,6, 6-tetramethylpiperidine-N-oxyl (TEMPONE): C. Kroll & H.H. Borchert; Eur. J. Pharm. Sci.
8, 5 (1999),
Abstract;
Characterization of the 4-oxo-2,2,6,6-tetramethylpiperidinooxy dosimeter for in situ radiolysis electron spin resonance studies: K.P. Madden; Radiat. Res.
147, 335 (1997),
Abstract;
Cytotoxicity of spin trapping compounds: R.F. Haseloff, et al.; FEBS Lett.
418, 73 (1997),
Abstract;
Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis: A.F. Slater, et al.; Biochem. J.
306, 771 (1995),
Abstract;
Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol: J.B. Mitchell, et al.; Arch. Biochem. Biophys.
289, 62 (1991),
Abstract;
Biologically active metal-independent superoxide dismutase mimics: J.B. Mitchell, et al.; Biochemistry
29, 2802 (1990),
Abstract;
Superoxide reaction with nitroxides: A. Samuni, et al.; Free Rad. Res. Commun.
9, 241 (1990),
Abstract;
Cytotoxicity of commonly used nitroxide radical spin probes: E.G. Ankel, et al.; Life Sci.
40, 495 (1987),
Abstract;
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