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TEMPONE-H . hydrochloride

Spin trapping reagent
ALX-430-071-M250 250 mg Inquire for pricing
ALX-430-071-M050 50 mg Inquire for pricing
ALX-430-071-M010 10 mg Inquire for pricing
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Very effective, cell permeable and non-toxic spin trap for the detection of superoxide radical and peroxynitrite.

Product Details

Alternative Name:1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine . HCl
Formula:C9H17NO2 . HCl
MW:171.2 . 36.5
Purity:≥99% (GLC)
Appearance:White to off-white crystalline powder.
Solubility:Soluble in DMSO, water, methanol or 100% ethanol.
Shipping:Blue Ice
Long Term Storage:-20°C
Use/Stability:Stable for at least two years after receipt when stored at -20°C.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Dynamic Wood Smoke Aerosol Toxicity during Oxidative Atmospheric Aging: S. Wang, et al.; Environ. Sci. Technol. 3, 1246 (2023), Abstract;
Biomonitoring Pilot Study in Workers from a Paints Production Plant Exposed to Pigment-Grade Titanium Dioxide (TiO2): E. Bergamaschi, et al.; Toxics 10, 171 (2022), Abstract;
Changes of physico-chemical properties of nano-biomaterials by digestion fluids affect the physiological properties of epithelial intestinal cells and barrier models: G. Antonello, et al.; Part. Fibre Toxicol. 19, 49 (2022), Abstract;
Therapeutic targeting of mitochondrial superoxide in hypertension: A.E. Dikalova, et al.; Circ. Res. 107, 106 (2010), Abstract;
Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine: S. Dikalov, et al.; BBRC 230, 54 (1997), Abstract;
Quantification of superoxide radicals and peroxynitrite in vascular cells using oxidation of sterically hindered hydroxylamines and electron spin resonance: S. Dikalov, et al.; Nitric Oxide Biol. Chem. 1, 423 (1997), Abstract;
Spin trapping of superoxide radicals and peroxynitrite by 1-Hydroxy-3-carboxy-pyrrolidine and 1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine and the stability of corresponding nitroxyl radicals towards biological reductants: S. Dikalov, et al.; BBRC 231, 701 (1997), Abstract;

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