Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

PDI monoclonal antibody (1D3) (PE conjugate)

ADI-SPA-891PE-D 50 µg 499.00 USD
ADI-SPA-891PE-F 200 µg 672.00 USD
Do you need bulk/larger quantities?

Product Details

Alternative Name:P4HB, protein disulfide isomerase
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of rat PDI.
UniProt ID:P04785
Source:Purified from ascites
Species reactivity:Human, Mouse, Rat
Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep, Xenopus
Applications:Flow Cytometry
Recommended Dilutions/Conditions:Flow Cytometry (1:100)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~58kDa by Western blot.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles. Protect from light.
Shipping:Blue Ice Not Frozen
Long Term Storage:+4°C
Scientific Background:The mammalian protein disulphide-isomerase (PDI) family encompasses several highly divergent proteins involved in the processing and maturation of secretory proteins in the ER by catalyzing the rearrangement of disulphide bonds. PDI, an abundant protein of the ER (>400uM), contains a carboxy-terminal retention signal sequence, KDEL, similar to that of BiP and Grp94. The PDI proteins are characterized by the presence of one or more domains of ~95-110 amino acids related to the cytoplasmic protein thioredoxin. All but the PDI-D subfamily are composed entirely of repeats of such domains, with at least one domain containing - and one domain lacking - a redox-active-Cys-X-X-Cys-tetrapeptide. In addition to roles as redox catalysts and isomerases, PDI proteins perform such functions as peptide binding and cell adhesion, and may conduct chaperone activities. Platelet surface thiols and disulphides play an important role in platelet responses. Catalytically active PDI resides on platelet surfaces where it mediates platelet aggregation and secretion by reducing disulfide bonds, thus exposing fibrinogen receptors in platelets.
Regulatory Status:RUO - Research Use Only
PDI monoclonal antibody (1D3) (PE conjugate) Flow Cytometry
Flow cytometry analysis of 106 Jurkat cells stained using PDI mAb (1D3), R-Phycoerythrin Conjugate at a concentration of 10µg/ml.
Please mouse over
PDI monoclonal antibody (1D3) (PE conjugate) Flow Cytometry

Product Literature References

Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione: F. Xiao, et al.; Nitric Oxide 25, 303 (2011), Application(s): FC analysis with human platelets, HCAEC and HCASMC, Abstract; Full Text

Related Products

Jurkat, (cell lysate) 

Human, WB | Print as PDF
ADI-LYC-JK100-F 200 µg 143.00 USD
Do you need bulk/larger quantities?

Goat anti-mouse IgG F(ab')2, polyclonal antibody (HRP conjugate) 

ELISA, IHC, WB | Print as PDF
ADI-SAB-100-J 1 ml 154.00 USD
Do you need bulk/larger quantities?

Mouse IgG1 isotype control, monoclonal antibody (MOPC-21) (PE conjugate) 

Purified from ascites., Flow Cytometry | Print as PDF
ADI-SAB-600PE-D 50 µg 256.00 USD
ADI-SAB-600PE-F 200 µg 528.00 USD
Do you need bulk/larger quantities?

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
PDI Monoclonal antibody
By catalog section:


Technical Service
Customer Service

Related Literature

Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Download as PDF

All new literature pieces