Alternative Name: | HSP70 cofactor, HSP24 |
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Host: | Rabbit |
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Immunogen: | Purified E. coli GrpE. |
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UniProt ID: | P09372 (strain K12) |
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GenBank ID: | X07863 |
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Source: | Purified from rabbit serum. |
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Species reactivity: | E. coli
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Applications: | WB
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Recommended Dilutions/Conditions: | Western Blot (1:1,000, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~24kDa by Western blot. |
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Purity Detail: | Protein A affinity purified. |
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Formulation: | Liquid. In PBS containing 50% glycerol and 0.09% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | GrpE (Glucose Regulated Protein E. coli) is encoded by a monocistronic E. coli gene, which is under the control of both s32 and s70 transcription factors. The GrpE protein is a so-called co-chaperone because it is known to assist the DnaK (Hsp70) protein to effectively carry out DnaK-dependent chaperone activity (i.e. protein folding, protein transport, disaggregation of heat inactivated proteins, activation of mutant protein). |
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Regulatory Status: | RUO - Research Use Only |
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