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EC SOD polyclonal antibody

ADI-SOD-106-D 50 µg 213.00 USD
ADI-SOD-106-F 200 µg 441.00 USD
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Product Details

Alternative Name:Superoxide Dismutase, SOD3
Immunogen:Synthetic peptide corresponding to a portion of EC SOD. The sequence is completely conserved in human, mouse, rat and rabbit.
UniProt ID:P08294
Source:Purified from rabbit serum.
Species reactivity:Human, Mouse, Rat
Recommended Dilutions/Conditions:Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~35-40kDa (glycosylation dependent) by Western blot.
Purity Detail:Protein A affinity purified.
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:SOD (Superoxide dismutase) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells, they are: EC SOD (extracellular SOD), Cu/Zn SOD (copper and zinc-containing SOD) and Mn SOD (manganese-containing SOD).
Regulatory Status:RUO - Research Use Only
EC SOD polyclonal antibody Western blot
Western blot analysis of EC SOD: Lane 1: MW Marker, Lane 2: Rat Lung Tissue Extract, Lane 3: Mouse Lung Tissue Extract, Lane 4: Human EC SOD Protein.
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EC SOD polyclonal antibody Western blot

Product Literature References

Potential Role of Superoxide Dismutase 3 (SOD3) in Resistance to Influenza A Virus Infection: F. Chen, et al.; Antioxidants 12, 354 (2023), Abstract;
Cerebrovascular endothelial dysfunction induced by mercury exposure at low concentrations: G.A. Wiggers, et al.; Neurotoxicology 53, 282 (2016), Application(s): Western blot, Abstract;
Extracellular Superoxide Dismutase Protects against Proteinuric Kidney Disease: R.J. Tan, et al.; J. Am. Soc. Nephrol. 26, 2447 (2015), Application(s): IHC on FFPE human kidney sections, Abstract; Full Text
MAPK pathway activation by chronic lead-exposure increases vascular reactivity through oxidative stress/cyclooxygenase-2-dependent pathways: M.R. Simões, et al.; Toxicol. Appl. Pharmacol. 283, 127 (2015), Application(s): Western Blotting, Abstract;
Hydrocortisone normalizes phosphodiesterase-5 activity in pulmonary artery smooth muscle cells from lambs with persistent pulmonary hypertension of the newborn: M. Perez, et al.; Pulm. Circ. 4, 71 (2014), Application(s): WB using fetal lamb pulmonary arterial smooth muscle cell (FPASMC) lysates, Abstract; Full Text
Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein: L.V. d'Uscio, et al.; Cardiovasc. Res. 96, 504 (2012), Application(s): Western Blot of mouse aorta lysates, Abstract; Full Text
Low mercury concentrations cause oxidative stress and endothelial dysfunction in conductance and resistance arteries: M. Salaices, et al. ; Am. J. Physiol. Heart Circ. Physiol. 295, H1033 (2008), Application(s): WB using rat tissue, Abstract;

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