Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

HIF-1α monoclonal antibody (Hα111a)

ADI-OSA-602-E 100 µg 379.00 USD
Do you need bulk/larger quantities?

Product Details

Alternative Name:Hypoxia-inducible factor 1α, ARNT-interacting protein
Immunogen:Recombinant human HIF-1α.
UniProt ID:Q16665
Source:Purified from hybridoma tissue culture supernatant.
Species reactivity:Human
Applications:IHC, WB
Recommended Dilutions/Conditions:Western Blot (4µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~120kDa by Western blot.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex which regulates systemic, local and intracellular homeostatic responses elicited by hypoxia. HIF-1 is a heterodimer of HIF-1alpha and HIF-1beta. HIF-1beta is constitutively expressed and serves as a dimerization partner for several other transcription factors, while HIF-1alpha and the closely related HIF-2 are unique to HIF-1 and their expression is tightly regulated by cellular oxygen concentration. HIF-1 regulates a diverse group of genes, including erythropoietin, VEGF, glucose transporters, heme oxygenase, and NOS.
Technical Info/Product Notes:Recommended by the Human Protein Atlas Organization for IHC (Ensembl No. ENSG00000100644).
Regulatory Status:RUO - Research Use Only
HIF-1α monoclonal antibody (Hα111a) Western blot
Western blot analysis of HIF-1α, mAb (Hα111a) (Prod. No. ADI-OSA-602): Lane 1: HeLa Cell Lysate (Prod. No. ADI-LYC-HL100), Lane 2: HeLa+CoCl2 Cell Lysate.
Please mouse over
HIF-1α monoclonal antibody (Hα111a) Western blot

Product Literature References

Potential role of CXCR4 in trastuzumab resistance in breast cancer patients: R.M. Kotb, et al.; Biochim. Biophys. Acta Mol. Basis Dis. 1868, 166520 (2022), Abstract;
Metabolic characteristics distinguishing intrahepatic cholangiocarcinoma: a negative pilot study of 18F-fluorocholine PET/CT clarified by transcriptomic analysis: S.A. Kwee, et al.; Am. J. Nucl. Med. Mol. Imaging 6, 73 (2016), Application(s): Immunohistochemistry, Abstract; Full Text
Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition: K.P. Ng, et al.; Blood 123, 3316 (2014), Application(s): Immunohistochemistry, Abstract;

Related Products

Goat anti-mouse IgG F(ab')2, polyclonal antibody (HRP conjugate) 

ELISA, IHC, WB | Print as PDF
ADI-SAB-100-J 1 ml 154.00 USD
Do you need bulk/larger quantities?

HeLa, (cell lysate) 

Human, WB | Print as PDF
ADI-LYC-HL100-F 200 µg 141.00 USD
Do you need bulk/larger quantities?

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
HIF Monoclonal antibody
By catalog section:


Technical Service
Customer Service

Related Literature

Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Download as PDF

All new literature pieces