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PKA (CT) polyclonal antibody

ADI-KAS-PK017-D 50 µg 199.00 USD
ADI-KAS-PK017-F 200 µg 457.00 USD
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Product Details

Alternative Name:Protein Kinase A
Immunogen:Synthetic peptide corresponding to a portion of human PKA.
UniProt ID:P17612 (Cα subunit), P22694 (Cβ subunit), P22162 (Cγ subunit), P10644 (RIα subunit), P31321 (RIβ subunit), P13861 (RIIα subunit), P31323 (RIIβ subunit)
Source:Purified from rabbit serum.
Species reactivity:Human, Mouse, Rat
Bovine, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep, Xenopus
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~40kDa by Western blot.
Purity Detail:Protein A affinity purified.
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:PKA (Protein Kinase A), also known as cAMP-dependent protein kinase, phosphorylates serine or threonine residues in target protein in response to elevated levels of cAMP. Inactive PKA exists as a tetrameric protein composed of two regulatory (R) subunits and two catalytic (C) subunits. Activation occurs when two cAMP molecules bind to each R subunit which causes a conformational change that releases the active C subunits.
Regulatory Status:RUO - Research Use Only
PKA (CT) polyclonal antibody Western blot
Western blot analysis of PKA: Lane 1: MW marker, Lane 2: CHO-K1, Lane 3: Mouse Brain, Lane 4: Rat Brain, Lane 5: HeLa, Lane 6: 3T3, Lane 7: PC-12.
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PKA (CT) polyclonal antibody Western blot

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