Product Details
| Alternative Name: | UNC-5 Homolog B, UNC5H2, UNC-5 Homolog 2, P53RDL1, p53-regulated receptor for death and life protein 1 |
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| Clone: | Guido-1 |
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| Host: | Mouse |
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| Isotype: | IgG2b |
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| Immunogen: | Recombinant human UNC5B (aa 28-363). |
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| UniProt ID: | Q8IZJ1 |
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| Source: | Purified from hybridoma tissue culture supernatant. |
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| Species reactivity: | Human, Mouse
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| Applications: | Flow Cytometry, WB
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| Recommended Dilutions/Conditions: | Western Blot (1:1000)
Suggested dilutinos/conditions may not be available for all application. Optimal conditions must be determined individually for each appplication. |
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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| Use/Stability: | Stable for 12 months after receipt when stored as recommended. |
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| Handling: | For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Protect from light. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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General Literature References
p53, apoptosis and axon-guidance molecules: H. Arakawa; Cell Death Differ.
12, 1057 (2005),
Abstract;
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system: X. Lu, et al.; Nature
432, 179 (2004),
Abstract;
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment: K. Thiebault, et al.; PNAS
100, 4173 (2003),
Abstract;
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