Product Details
Alternative Name: | UNC-5 Homolog B, UNC5H2, UNC-5 Homolog 2, P53RDL1, p53-regulated receptor for death and life protein 1 |
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Clone: | Guido-1 |
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Host: | Mouse |
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Isotype: | IgG2b |
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Immunogen: | Recombinant human UNC5B (aa 28-363). |
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UniProt ID: | Q8IZJ1 |
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Source: | Purified from ascites. |
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Species reactivity: | Human, Mouse
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Applications: | Flow Cytometry
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Purity Detail: | Protein G-affinity purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Use/Stability: | Stable for at least 1 year after receipt when stored as recommended. |
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Handling: | For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Protect from light. |
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Shipping: | Blue Ice |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development: T. Tu, et al.; Cell Res.
25, 275 (2015),
Abstract;
Full Text
General Literature References
p53, apoptosis and axon-guidance molecules: H. Arakawa; Cell Death Differ.
12, 1057 (2005),
Abstract;
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system: X. Lu, et al.; Nature
432, 179 (2004),
Abstract;
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment: K. Thiebault, et al.; PNAS
100, 4173 (2003),
Abstract;