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UNC5B monoclonal antibody (Guido-1)

ALX-804-846-C100 100 µg 396.00 USD
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Product Details

Alternative Name:UNC-5 Homolog B, UNC5H2, UNC-5 Homolog 2, P53RDL1, p53-regulated receptor for death and life protein 1
Immunogen:Recombinant human UNC5B (aa 28-363).
UniProt ID:Q8IZJ1
Source:Purified from ascites.
Species reactivity:Human, Mouse
Applications:Flow Cytometry
Purity Detail:Protein G-affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
Handling:For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Protect from light.
Shipping:Shipped on Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development: T. Tu, et al.; Cell Res. 25, 275 (2015), Abstract; Full Text

General Literature References

p53, apoptosis and axon-guidance molecules: H. Arakawa; Cell Death Differ. 12, 1057 (2005), Abstract;
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system: X. Lu, et al.; Nature 432, 179 (2004), Abstract;
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment: K. Thiebault, et al.; PNAS 100, 4173 (2003), Abstract;

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