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PATHO-GENE® HPV type 6/11 probe

A mixture of biotin-labeled HPV 6 and HPV 11-specific probes for in situ hybridization
 
ENZ-32885-6000 6 ml Inquire for pricing
 
ENZ-32885 1 ml 852.00 USD
Do you need bulk/larger quantities?
 
The PATHO-GENE® HPV type 6/11 probe is a mixture of biotin-labeled HPV 6 and HPV 11-specific probes in buffered formamide and hybridization enhancers.

Product Specification

Application Notes:The ENZO PATHO-GENE® HPV type 6/11 probe employs a mixture of the HPV 6 and HPV 11-specific probes that detect HPV types that have been associated with benign lesions presenting as condylomas and mild dysplasia. The probe mixture is denatured and hybridized to the tissue section fixed and pretreated on the microscope slide. Specific hybridization between the HPV DNA probe and DNA in the specimen is determined by the detection of biotin.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Use/Stability:Stable for at least one year after receipt when stored as recommended.
 
Technical Info/Product Notes:HPV probe can be optimized for polymer detection system using diluent buffer, In situ hybridization buffer for HPV probes (Ready-to Use) (Prod. No. ENZ-33905).

This product or the use of this product is covered by one or more Enzo patents, including, but not limited to the following: U.S. Patent No. 4,994,373; Canadian Patent No. 1,309,672; and patents pending.
 

Product Literature References

Automated In Situ Hybridization For Human Papilloma Virus: C. Cohen, et al.; Appl. Immunohistochem. Mol. Morphol. 22, 619 (2014), Abstract;
The utility of in situ detection, including RT in situ PCR, of viral nucleic acid and the co-localization of the cytokine response to the study of viral pathogenesis: S.M. Amaro Filho, et al.; Methods 52, 332 (2010), Abstract;
p16 expression in relation to human papillomavirus in liquid-based cervical smears: B. Samama, et al.; Gynecol. Oncol. 109, 285 (2008), Abstract;
Time course of juvenile onset recurrent respiratory papillomatosis caused by human papillomavirus: M. Hawkes, et al.; Pediatr. Infect. Dis. J. 27, 149 (2008), Abstract;
p16 expression in relation to human papillomavirus in anogenital lesions: B. Samama, et al.; Hum. Pathol. 37, 513 (2006), Abstract;
Comparison of real-time PCR signal-amplified in situ hybridization and conventional PCR for detection and quantification of human papillomavirus in archival cervical cancer tissue: K. Biedermann, et al.; J. Clin. Microbiol. 42, 3758 (2004), Abstract;
A cardiac allograft recipient with Bowen's disease on a finger and concurrent perianal bowenoid papulosis: M. Ibe, et al.; J. Dermatol. 30, 389 (2003), Abstract;
DNA copy number changes in cervical adenocarcinoma: A. Dellas, et al.; Clin. Cancer Res. 9, 2985 (2003), Abstract;
Morphologic and biologic studies on ten cases of verrucous carcinoma of the vulva supporting the theory of a discrete clinico-pathologic entity: M. Gualco, et al.; Int. J. Gynecol. Cancer 13, 317 (2003), Abstract;
Pearly penile papules: still no reason for uneasiness: C.J. Hogewoning, et al.; J. Am. Acad. Dermatol. 49, 50 (2003), Abstract;
Detection of kappa- and lambda-expressing cells in the endometrium by in situ hybridization: E. Euscher, et al.; Int. J. Gynecol. Pathol. 21, 383 (2002), Abstract;
HPV DNA detection by in situ hybridization with catalyzed signal amplification on thin-layer cervical smears: B. Samama, et al.; J. Histochem. Cytochem. 50, 1417 (2002), Abstract;
Penile lesions and human papillomavirus in male sexual partners of women with cervical intraepithelial neoplasia: M.C. Bleeker, et al.; J. Am. Acad. Dermatol. 47, 351 (2002), Abstract;
Primary inverted papilloma of the middle ear and mastoid: C. de Filippis, et al.; Otol. Neurotol. 23, 555 (2002), Abstract;
Squamous cell carcinomas arising from adnexal ductal cysts: H.G. Skelton, et al.; Arch. Pathol. Lab. Med. 126, 76 (2002), Abstract;
Human papillomaviruses 6/11, 16/18 and 31/33/51 are not associated with squamous cell carcinoma of the urinary bladder: P.J. Westenend, et al.; BJU Int. 88, 198 (2001), Abstract;
Significance of human papillomavirus in sinonasal papillomas: M. Kraft, et al.; J. Laryngol. Otol. 115, 709 (2001), Abstract;
Squamous papilloma of the esophagus: long-term follow up: S. Mosca, et al.; J. Gastroenterol. Hepatol. 16, 857 (2001), Abstract;
MIB-1 immunostaining is a beneficial adjunct test for accurate diagnosis of vulvar condyloma acuminatum: E.C. Pirog, et al.; Am. J. Surg. Pathol. 24, 1393 (2000), Abstract;
Squamous papilloma of the urinary tract is unrelated to condyloma acuminata: L. Cheng, et al.; Cancer 88, 1679 (2000), Abstract;
Detection of human papillomavirus by in situ polymerase chain reaction in paraffin-embedded cervical biopsies: C. Bernard, et al. ; Mol. Cell. Probes 8, 337 (1994), Application(s): in situ hybridization, Abstract;
Evaluation of Biohit HPV Screening and Typing kits in detection of human papillomavirus DNA from lesions of anogenital tract: C. Bernard, et al.; Diagn. Mol. Pathol. 3, 192 (1994), Application(s): in situ hybridization, Abstract;
Nucleolar organizer regions and cervical intraepithelial neoplasia among women with human immunodeficiency virus infection: A. Spinillo, et al.; Am. J. Obstet. Gynecol. 171, 773 (1994), Application(s): in situ hybridization, Abstract;
Squamous cell papillomas of the esophagus: a study of 23 lesions for human papillomavirus by in situ hybridization and the polymerase chain reaction: N.J. Carr, et al.; Hum. Pathol. 25, 536 (1994), Application(s): in situ hybridization, Abstract;
Langerhans' cell counts and cervical intraepithelial neoplasia in women with human immunodeficiency virus infection: A. Spinillo, et al.; Gynecol. Oncol. 48, 210 (1993), Application(s): in situ hybridization, Abstract;
Use of Probemix and OmniProbe biotinylated cDNA probes for detecting HPV infection in biopsy specimens from the genital tract: I. Zehbe, et al.; J. Clin. Pathol. 46, 437 (1993), Application(s): in situ hybridization, Abstract; Full Text
A comparison of histopathologic diagnosis and the demonstration of human papillomavirus-specific DNA and proteins in penile warts: J. Lassus, et al.; Sex Transm. Dis. 19, 127 (1992), Application(s): in situ hybridization, Abstract;
Chromosome fragility in lymphocytes of women with cervical uterine lesions produced by human papillomavirus: C. Paz-y-Miño, et al.; Cancer Genet. Cytogenet. 59, 173 (1992), Application(s): in situ hybridization, Abstract;
Comparison of four in situ hybridization methods, based on digoxigenin- and biotin-labelled probes, in detecting HPV DNA in male condylomata acuminata: J. Lassus, et al.; Int. J. STD AIDS 3, 196 (1992), Application(s): in situ hybridization, Abstract;
Correlation of the expression of Epstein-Barr virus latent membrane protein and in situ hybridization with biotinylated BamHI-W probes in Hodgkin's disease: G. Delsol, et al.; Am. J. Pathol. 140, 247 (1992), Application(s): negative controls, Abstract; Full Text
Demonstration of human papillomavirus DNA in a peripheral ameloblastoma by in situ hybridization: M.A. Kahn, et al.; Hum. Pathol. 23, 188 (1992), Application(s): in situ hybridization, Abstract;
Effect of human papillomavirus infection on estrogen receptor and heat shock protein hsp27 phenotype in human cervix and vagina: D.R. Ciocca, et al.; Int. J. Gynecol. Pathol. 11, 113 (1992), Application(s): in situ hybridization, Abstract;
Human papillomavirus infection and anal carcinoma. Retrospective analysis by in situ hybridization and the polymerase chain reaction: S.R. Zaki, et al.; Am. J. Pathol. 140, 1345 (1992), Application(s): in situ hybridization, Abstract; Full Text
Superficial nuclear enlargement without koilocytosis as an expression of human papillomavirus infection of the uterine cervix: an in situ hybridization study: G.C. Yang, et al.; Int. J. Gynecol. Pathol. 11, 283 (1992), Application(s): in situ hybridization, Abstract;
Adenoacanthoma of the endometrium: morphological changes induced by human papillomavirus: W.F. Kealy, et al.; J. Clin. Pathol. 43, 554 (1990), Application(s): in situ hybridization, Abstract; Full Text
A rapid DNA probe test for detecting human papilloma virus types 6/11 and 16 in biopsy specimens: J.A. Todd, et al.; Mol. Cell. Probes 3, 273 (1989), Application(s): in situ hybridization, Abstract;
Sensitivity of in situ detection with biotinylated probes of human papilloma virus type 16 DNA in frozen tissue sections of squamous cell carcinomas of the cervix: J.M. Walboomers, et al.; Am. J. Pathol. 131, 587 (1988), Abstract;
Detection of viral genomes in cultured cells and paraffin-embedded tissue sections using biotin-labeled hybridization probes: D.J. Brigati, et al.; Virology 126, 32 (1983), Abstract;
Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes: P.R. Langer, et al.; PNAS 78, 6633 (1981), Abstract;

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