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ODN 1826 (TLRGRADE™) (synthetic) (BULK)

TLR9 ligand
 
ALX-746-052-M001 1 mg 560.00 USD
Do you need bulk/larger quantities?
 
For a smaller pack size, please see Prod. No. ALX-746-002.
CpG oligodeoxynucleotide (Type B) with phosphorothioate backbone. Specific ligand for mouse TLR9 (Toll-like receptor 9).

Product Specification

Alternative Name:CpG-B
 
Sequence:5’-tccatgacgttcctgacgtt-3’ (lower case letters indicate phosphorothioate linkage).
 
MW:6383 (ammonium salt)
 
Source:Synthetic.
 
Quantity:157.5nmol
 
Formulation:Lyophilized. Sterile.
 
Purity Detail:Activity and endotoxin tested - TLRGRADE™.
 
Endotoxin Content:<0.002EU/µg (LAL test; BioWhittaker)
 
Reconstitution:For a 200µM stock solution, dissolve the total vial content in 788µl endotoxin-free ddWater (Prod. No. ALX-505-008) or endotoxin-free PBS (Prod. No. ALX-505-007). To obtain optimal dissolving we recommend the following procedure:
- Add 50% of the solvent and let dissolve for 10 min.
- Add remaining 50% of the solvent and mix thoroughly.
- Moderate warming may aid dissolving.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Use/Stability:Aqueous stock solution is stable for 1 day when stored at +4°C.
 
Technical Info/Product Notes:Includes 1 vial of ddWater (endotoxin-free) (Prod. No. ALX-505-008).
For the inactive control compound, please see Prod. No. ALX-746-201.
 

Product Literature References

Enhancing radiosensitivity of human pulmonary adenocarcinoma cell line A549 by CpG ODN1826: R. Li, et al.; Cancer Biother. Radiopharm. 26, 69 (2011), Abstract;

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