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Synaptotagmin monoclonal antibody (ASV30)

 
ADI-SYA-130-D 50 µg 184.00 USD
 
ADI-SYA-130-F 200 µg 399.00 USD
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Product Specification

Alternative Name:SYT
 
Clone:ASV30
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Rat brain synaptic junction protein complexes .
 
UniProt ID:P21707
 
GenBank ID:X52772
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~65kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Synaptotagmins (Syt) are membrane-trafficking proteins characterized by an N-terminal transmembrane region, a variable linker, and two C-terminal C2-domains, C2A and C2B. At least twelve Synaptotagamins are expressed in vertebrates and can be found in both vesicular and plasma membranes.
 
SYA-130 WB 01
Western blot analysis of Synaptotagmin: Lane 1: MW marker, Lane 2: Mouse Brain Tissue Lysate (Prod No. ADI-LYT-MB100), Lane 3: Rat Brain Tissue Lysate (Prod No. ADI-LYT-RB100).
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SYA-130 WB 01

Product Literature References

Botulinum neurotoxin A activity is dependent upon the presence of specific gangliosides in neuroblastoma cells expressing synaptotagmin I: C.L. Schengrund, et al. ; J. Biol. Chem. 277, 32815 (2002), Application(s): WB using human & mouse samples, Abstract;
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecterory tissue: W.D. Matthew, et al.; J. Cell Biol. 91, 257 (1981), Application(s): WB, IHC using rat samples, Abstract;

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