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Synaptotagmin monoclonal antibody (ASV30)

ADI-SYA-130-D 50 µg 194.00 USD
ADI-SYA-130-F 200 µg 419.00 USD
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Product Specification

Alternative Name:SYT
Immunogen:Rat brain synaptic junction protein complexes .
UniProt ID:P21707
GenBank ID:X52772
Source:Purified from mouse ascites.
Species reactivity:Human, Mouse, Rat
Applications:IHC, WB
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~65kDa by Western blot.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Synaptotagmins (Syt) are membrane-trafficking proteins characterized by an N-terminal transmembrane region, a variable linker, and two C-terminal C2-domains, C2A and C2B. At least twelve Synaptotagamins are expressed in vertebrates and can be found in both vesicular and plasma membranes.
Synaptotagmin monoclonal antibody (ASV30) Western blot
Western blot analysis of Synaptotagmin: Lane 1: MW marker, Lane 2: Mouse Brain Tissue Lysate (Prod No. ADI-LYT-MB100), Lane 3: Rat Brain Tissue Lysate (Prod No. ADI-LYT-RB100).
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Synaptotagmin monoclonal antibody (ASV30) Western blot

Product Literature References

Botulinum neurotoxin A activity is dependent upon the presence of specific gangliosides in neuroblastoma cells expressing synaptotagmin I: C.L. Schengrund, et al. ; J. Biol. Chem. 277, 32815 (2002), Application(s): WB using human & mouse samples, Abstract;
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecterory tissue: W.D. Matthew, et al.; J. Cell Biol. 91, 257 (1981), Application(s): WB, IHC using rat samples, Abstract;

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