| ENZ-ABS737-0100 | 100 µl | 445.00 USD |  |
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| Alternative Name: | Programmed cell death 1, CD279, Programmed death receptor 1 |
| Clone: | 4F12 |
| Host: | Mouse |
| Isotype: | IgG2bκ |
| Immunogen: | Recombinant human PDCD1 (aa 21-167) purified from E. coli. |
| UniProt ID: | Q15116 |
| Source: | Purified from ascites. |
| Species reactivity: | Human |
| Applications: | ELISA, Flow Cytometry, ICC, IF, WB |
| Recommended Dilutions/Conditions: | Western Blot (1:500). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Protein G affinity purified |
| Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. |
| Regulatory Status: | RUO - Research Use Only |
