Positively charged rhodamine dyes (such as rhodamine esters and rosamines) are selectively localized in mitochondria, thus they are widely used for labeling mitochondria of live cells. Like JC-1,TMRE is widely used for measuring mitochondrial membrane potential, in addition to selectively staining mitochondria. Real-time imaging of mitochondrial membrane potential in individual cardiomyocytes within perfused rat hearts has been demonstrated with this dye, using 2-photon laser-scanning microscopy. Wavelength Maxima: Excitation 549nm, Emission 574nm
Product Details
Alternative Name: | Tetramethylrhodamine ethyl ester perchlorate, 3,6-bis(Dimethylamino)-9-[2-(ethoxycarbonyl)phenyl]-xanthylium perchlorate |
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Formula: | C26H27ClN2O7 |
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MW: | 515.0 |
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CAS: | 115532-52-0 |
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Purity: | ≥95% (HPLC) |
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Solubility: | Soluble in DMSO. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -20°C |
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Use/Stability: | Stable for at least one year after receipt when stored as recommended. |
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Handling: | Protect from light. Keep cool and dry. |
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Technical Info/Product Notes: | This product is a member of the CELLESTIAL® product line, reagents and assay kits comprising fluorescent molecular probes that have been extensively benchmarked for live cell analysis applications. CELLESTIAL® reagents and kits are optimal for use in demanding imaging applications, such as confocal microscopy, flow cytometry and HCS, where consistency and reproducibility are required. |
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Regulatory Status: | RUO - Research Use Only |
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