Product Details
Clone: | HP810 |
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Host: | Mouse |
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Isotype: | IgG |
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Immunogen: | Human erythrocyte-derived proteasomes. |
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Species reactivity: | Human
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Specificity: | Recognizes the α subunit of the 20S proteasome. |
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Applications: | ICC, IF, IP
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Recommended Dilutions/Conditions: | Immunofluorescence (5-10µg/ml)
Immunoprecipitation (1-2µg/107cell/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein G-affinity purified. |
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Formulation: | Liquid. In PBS containing 10mM sodium azide. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Proteins associated with the promyelocytic leukemia gene products (PML)-containing nuclear body move to the nucleus upon inhibition of proteasome-dependent protein degradation: K. Mattson, et al.; PNAS
98, 1012 (2001),
Abstract;
Full Text
General Literature References
Subunit arrangement in the human 20S proteasome: F. Kopp, et al.; PNAS
94, 2939 (1997),
Abstract;
Full Text
The 26S proteasome: subunits and functions: K. Tanaka & C. Tsurumi; Mol. Biol. Rep.
24, 3 (1997), (Review),
Abstract;
Human proteasomes analysed with monoclonal antibodies: K.B. Hendil, et al.; Biochem. J.
305, 245 (1995),
Abstract;
Full Text