A novel geldanamycin fluorescent probe that may be used in a fluorescence polarization assay for HSP90 inhibitors. May also be used for detection of cell surface HSP90.
Product Details
| Formula: | C55H63N5O13S |
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| MW: | 1034.2 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Purple solid. |
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| Solubility: | Soluble in DMSO (>10mg/ml). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Development of a fluorescence polarization assay for the molecular chaperone Hsp90: J. Kim, et al.; J. Biomol. Screen
9, 375 (2006),
Abstract;
L.T. Gooljarsingh et al. Proc. Natl. Acad. Sci. USA 2006 103 7625: L.T. Gooljarsingh, et al.; Proc. Natl. Acad. Sci. USA
103, 7625 (2006),
Abstract;
Synthesis of novel fluorescent probes for the molecular chaperone Hsp90: L. Llauger-Bufi, et al. ; Bioorg. Med. Chem. Lett.
13, 3975 (2003),
Abstract;
