Inhibitor of 5-lipoxygenase (ID50=4 µM) and 12-lipoxygenase (ID50=2.5 µM). Does not inhibit cyclooxygenase.
Product Details
| Alternative Name: | 6,7-Dihydroxycoumarin |
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| Formula: | C9H6O4 |
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| MW: | 178.1 |
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| CAS: | 305-01-1 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white crystalline solid. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesis: T. Neichi, et al.; Biochim. Biophys. Acta.
753, 130 (1983),
Abstract;
