Product Details
| Alternative Name: | BCL2L2 |
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| Clone: | 16H12 |
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| Host: | Rat |
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| Isotype: | IgG2a |
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| Immunogen: | Recombinant human Bcl-w. |
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| UniProt ID: | Q92843 |
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| Species reactivity: | Human, Mouse, Rat
Dog, Monkey
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| Applications: | IP, WB
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Liquid. In PBS containing 25% glycerol and 0.02% sodium azide. |
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| Use/Stability: | Stable for up to 3 months when stored at +4°C. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Technical Info/Product Notes: | Western Blot works for transfected and Bcl-w overproducing cells. For detection of endogenous Bcl-w, immunoprecipitation is required. |
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| Regulatory Status: | RUO - Research Use Only |
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Figure: Western blot showing the detection of Bcl-w in fractionated lysates of mouse tissues with clone 16H12. Antibody specificity is indicated by the absence of the expected 21 kDa protein in Bcl-w -/- testis control tissues. The 67 kDa band is Hsp-70 used as an equal loading control.
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Product Literature References
In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis: G. Cao, et al.; J. Neurosci.
22, 5423 (2002),
Abstract;
Tissue expression and subcellular localization of the pro-survival molecule Bcl-w: L.A. O'Reilly, et al.; Cell Death Differ.
8, 486 (2001),
Abstract;
Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine: D.M. Pritchard, et al.; Oncogene
19, 3955 (2000),
Abstract;
