Aminoglycoside antibiotic with similar structure to the kanamycins and the gentamycins. Used in the treatment of respiratory infection and cystic fibrosis.
Product Details
| Alternative Name: | Deoxykanamycin B, Distobram, Gernebcin, Obramycin, Tobradistin |
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| Formula: | C18H37N5O9 |
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| MW: | 467.5 |
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| Source: | Isolated from Streptomyces tenebarius. |
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| CAS: | 32986-56-4 |
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| MI: | 14: 9490 |
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| RTECS: | WK2100000 |
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| Formulation: | Free base. |
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| Appearance: | White to off-white powder. |
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| Activity: | ≥900µg/mg |
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| Solubility: | Soluble in water; very slightly soluble in 100% ethanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Tobramycin solution for inhalation in cystic fibrosis patients: a review of the literature: J.K. Hagerman, et al.; Expert Opin. Pharmacother.
8, 467 (2007), Review,
Abstract;
Inhaled tobramycin (TOBI): a review of its use in the management of Pseudomonas aeruginosa infections in patients with cystic fibrosis: S.M. Cheer, et al.; Drugs
63, 2501 (2003), Review,
Abstract;
Tobramycin: a review of its antibacterial and pharmacokinetic properties and therapeutic use: R. N. Brogden, et al.; Drugs
12, 166 (1976), Review,
Abstract;
