Replaces Prod. #: ALX-201-205/1
Product Details
Alternative Name: | BMP-2 |
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MW: | ~25.9kDa. |
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Source: | Produced in E. coli and renatured from inclusion body material. |
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UniProt ID: | P12643 |
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Concentration: | 100-500μg/ml after reconstitution. |
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Formulation: | Lyophilized. |
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Purity: | ≥98% (SDS-PAGE, UV, MS) |
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Endotoxin Content: | <0.02EU/mg protein. |
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Biological Activity: | Induces alkaline phosphatase expression at an EC50 = 14nM in C2C12 cells. |
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Reconstitution: | Reconstitute with 20-100μl 50mM sodium acetate solution, pH 4.3. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Use/Stability: | The reconstituted solution can be further diluted in sodium acetate solution and stored at +4°C for up to two weeks. Below 10μg/ml, 0.5% BSA or serum should be added. |
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Handling: | After reconstitution, prepare aliquots and store at -80°C. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Biophysical comparison of BMP-2, ProBMP-2, and the free pro-peptide reveals stabilization of the pro-peptide by the mature growth factor : F. Hillger, et al.; J. Biol. Chem.
280, 14974 (2005),
Abstract;
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