| ADI-CSA-509-E | 100 µg | 471.00 USD |  |
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| Alternative Name: | TIR-1, Sterile α and TIR motif-containing protein 1, SAM and ARM-containing protein, Sterile α motif and armadillo repeat-containing protein |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human SARM. |
| UniProt ID: | Q6SZW1 |
| Gene/Protein Identifier: | NP_055892 (RefSeq) |
| Species reactivity: | Human, Mouse |
| Applications: | ICC, WB |
| Recommended Dilutions/Conditions: | Immunocytochemistry (2µg/ml) Western Blot (0.5-2.0µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Ion exchange purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | SARM (SAM and ARM-containing protein) is thought to serve as an adaptor protein for the Toll-like receptors (TLRs) and allow for the activation of downstream kinases and NF-κB, ultimately leading to the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interleukin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule. |
| Regulatory Status: | RUO - Research Use Only |
