| Alternative Name: | CA2, Carbonic anhydrase II, CA-II, Car2 |
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| MW: | ~30 kDa |
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| Source: | Produced in HEK 293 cells. |
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| EC: | 4.2.1.1 |
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| UniProt ID: | P00918 |
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| Formulation: | Lyophilized from 0.22µm filtered solution in 20mM TRIS, pH 8.0, containing 150mM NaCl and 1mM DTT. Normally mannitol or trehalose is added as protectant before lyophilization. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Shipping: | Blue Ice |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Carbonic anhydrase 2 is essential for bone resorption and osteoclast differentiation. It catalyzes the reversible hydration of carbon dioxide. It can hydrate cyanamide to urea. It is also involved in the regulation of fluid secretion into the anterior chamber of the eye. Carbonic anhydrase contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Carbonic anhydrase 2 also stimulates the chloride-bicarbonate exchange activity of SLC26A6 |
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| Regulatory Status: | RUO - Research Use Only |
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