Trametinib is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays.
Product Details
| Formula: | C26H23FIN5O4 |
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| MW: | 615.4 |
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| CAS: | 871700-17-3 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White solid. |
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| Solubility: | Soluble in DMSO (20 mg/mL). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
CREB Is Activated by the SCF/KIT Axis in a Partially ERK-Dependent Manner and Orchestrates Survival and the Induction of Immediate Early Genes in Human Skin Mast Cells: K. Franke, et al.; Int. J. Mol. Sci.
24, 4135 (2023),
Abstract;
