PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with an IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on the phosphorylation of ERK1 and ERK2.
Product Details
| Alternative Name: | (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide |
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| Formula: | C16H14F3IN2O4 |
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| MW: | 482.2 |
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| CAS: | 391210-10-9 |
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| Purity: | ≥99% (HPLC) |
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| Identity: | Determined by NMR. |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in DMSO (12mg/ml) or ethanol (6.3mg/ml) with slight warming. |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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