MK-2206 is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC50 of 8 nM, 12 nM and 65 nM, respectively.
Product Details
| Formula: | C25H21N5O . 2HCl |
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| MW: | 480.4 |
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| CAS: | 1032350-13-2 |
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| Purity: | ≥99% (HPLC) |
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| Identity: | Determined by NMR |
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| Appearance: | Yellow powder. |
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| Solubility: | Soluble in DMSO (14mg/ml) or ethanol (1mg/ml). |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer’s disease models: M. Fassler, et al.; J. Neuroinflammation
18, 19 (2021),
Abstract;
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