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United States 

Dorsomorphin . hydrochloride

Potent and selective AMPK inhibitor.
ENZ-CHM141-0005 5 mg 159.00 USD
ENZ-CHM141-0010 10 mg 226.00 USD
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Potent and selective AMPK inhibitor. Dorsomorphin also inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK-2), BMPR-IA (ALK-3), and BMPR-IB (ALK-6).

Product Details

Alternative Name:6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Formula:C24H25N5O . 2 HCl
Purity:≥99% (HPLC)
Appearance:Light yellow powder solid.
Solubility:Soluble in DMSO or water.
Shipping:Ambient Temperature
Short Term Storage:-20°C
Long Term Storage:-80°C
Regulatory Status:RUO - Research Use Only
ENZ-CHM141 structure
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ENZ-CHM141 structure

Product Literature References

A temporal Ca 2+-desensitization of myosin light chain kinase in phasic smooth muscles induced by CaMKKß/PP2A pathways: T. Kitazawa, et al.; Am. J. Physiol. Cell Physiol. 321, C549 (2021), Abstract;
A rare human CEP290 variant disrupts the molecular integrity of the primary cilium and impairs Sonic Hedgehog machinery: M.B.C. Kilander, et al.; Sci. Rep. 8, 17355 (2018), Abstract; Full Text