A cell-permeable compound that acts as a potent, ATP-competitive, and reversible inhibitor of FGF and VEGF receptors. PD 173074 inhibits PDGFR and c-Src only at much higher concentration. Shown to inhibit the autophosphorylation of endogenous FGFR1 and overexpressed VEGFR2.
Product Details
| Alternative Name: | 1-t-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)-pyrido[2,3-d]pyrimidin-7-yl)urea |
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| Formula: | C28H41N7O3 |
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| MW: | 523.7 |
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| CAS: | 219580-11-7 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White powder solid. |
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| Solubility: | Soluble in DMSO or methanol. |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -80°C |
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| Regulatory Status: | RUO - Research Use Only |
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