| Alternative Name: | Coagulation factor XII, Hageman factor |
| |
| Clone: | 10-11-37 |
| |
| Host: | Mouse |
| |
| Isotype: | IgG2aκ |
| |
| Immunogen: | Affinity purified human factor XII. |
| |
| UniProt ID: | P00748 |
| |
| Source: | From culture supernatant. |
| |
| Species reactivity: | Human
|
| |
| Specificity: | Binds the heavy chain of human factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes. |
| |
| Applications: | ELISA, WB
|
| |
| Purity Detail: | Protein A/G-purified. |
| |
| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
| |
| Shipping: | Blue Ice Not Frozen |
| |
| Long Term Storage: | +4°C |
| |
| Scientific Background: | Factor XII is a component in the coagulation cascade. It is a plasma glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII to a-factor XIIa, which in turn activates factor XI to factor XIa. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
