Product Details
| Alternative Name: | Ubiquitin-specific protease 14 |
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| MW: | 56.1 kDa |
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| Source: | Produced in E. coli. |
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| UniProt ID: | P54578 |
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| Formulation: | Liquid. In 10mM TRIS containing 50mM NaCl and 1mM DTT, pH 7.4. |
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| Purity: | ≥90% (SDS-PAGE) |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | USP14 is a ubiquitin-specific protease. Little is known about the biological roles of substrates of USP14, but depletion of its homolog in mice cause defects in synaptic transmission. |
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| Regulatory Status: | RUO - Research Use Only |
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Western Blot analysis: Lane 1: MW marker, Lane 2: 100ng of purified USP-14 (human), (Recombinant) protein probed with USP-14 mAb.
SDS-PAGE analysis: Lane 1: MW marker, Lane 2: 2.0μg of purified USP-14 (human), (Recombinant) protein.
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Product Literature References
TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14: L. Chen, et al.; Nat. Commun.
9, 1223 (2018),
Abstract;
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