Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

14-3-3η (human), (recombinant) (His-tag)

BML-SE486-0100 100 µg 366.00 USD
Do you need bulk/larger quantities?

Product Details

MW:~30 kDa
Source:Produced in E. coli. Human 14-3-3η is fused at the C-terminus to a His-tag.
UniProt ID:Q04917
Formulation:Liquid. In 50mM NaH2PO4, pH 8.0, 300mM NaCl.
Purity:≥90% (SDS-PAGE)
Purity Detail:Purified by multi-step chromatography.
Application Notes:Drug screening, protein-protein interaction studies, gel overlays.
Shipping:Dry Ice
Long Term Storage:-80°C
Scientific Background:14-3-3 proteins are dimeric phosphoserine/phosphothreonine binding proteins, which have been shown to be involved in the regulation of many crucial processes such as signal transduction, cell-cycle control, apoptosis, protein localization, phosphorylation state and stability, transcription, metabolism, and malignant transformation. The expression of 14-3-3η was reported to be significantly reduced in the cerebella of transgenic mice overexpressing IGF-1 and was predominantly, if not exclusively, expressed in Purkinje cells. It has also been reported that 14-3-3η functions as a positive regulator in the glucocorticoid signal pathway.
Regulatory Status:RUO - Research Use Only

General Literature References

C-TAK1 interacts with microphthalmia-associated transcription factor, Mitf, but not the related family member Tfe3: T. Schwarz, et al.; BBRC 394, 890 (2010), Abstract;

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
14-3-3 Recombinant protein
By catalog section:


Technical Service
Customer Service

Related Literature

Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

All new literature pieces