Alternative Name: | Tumor necrosis factor-α, TNFSF 2 |
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MW: | 17.5 kDa |
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Source: | Produced in E. coli as a single, non-glycosylated polypeptide. |
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UniProt ID: | P01375 |
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Formulation: | Sterile, lyophilized powder. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Tumor necrosis factor is a multifunctional proinflammatory cytokine, with effects on lipid metabolism, coagulation, insulin resistance, endothelial function, autoimmune disease and allergic responses. TNF-β shares 35% identity and 50% homology in amino acid sequence with the TNF-α and it has been shown that the 2 TNFs share a common receptor on tumor cells. |
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Regulatory Status: | RUO - Research Use Only |
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