Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

2-Methoxyestradiol

Estrogen receptor inhibitor
 
BML-S540-0010 10 mg 93.00 USD
 
BML-S540-0050 50 mg 382.00 USD
Do you need bulk/larger quantities?
 
An endogenous estrogen metabolite with low affinity for the estrogen receptor but which disrupts microtubule function. Potent inhibitor of endothelial cell proliferation and migration. Inhibits bFGF and VEGF-induced corneal neovascularization in mice. Posttranscriptionally downregulates HIF-1α expression.

Product Details

Alternative Name:2-ME
 
Formula:C19H26O3
 
MW:302.4
 
CAS:362-07-2
 
Purity:≥95% (TLC)
 
Identity:Determined by 1H-NMR and MS.
 
Appearance:White solid.
 
Shipping:Ambient Temperature
 
Long Term Storage:Ambient
 
Regulatory Status:RUO - Research Use Only
 
BML-S540 structure
Please mouse over
BML-S540 structure

Product Literature References

To complete its replication cycle, a shrimp virus changes the population of long chain fatty acids during infection via the PI3K-Akt-mTOR-HIF1α pathway: Y.C. Hsieh, et al.; Dev. Comp. Immunol. 53, 85 (2015), Application(s): Injection into shrimp, Abstract;
Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy: S. Lorin, et al.; Autophagy 6, 153 (2010), Abstract;

Related Literature

Brochures
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Download as PDF

Brochures
Neurodegeneration
Neurodegeneration
Download as PDF

All new literature pieces