Product Details
| Alternative Name: | Proteasome activator complex subunit 3, PA28γ |
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| MW: | ~29.5 kDa |
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| Source: | Produced in E.coli. |
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| UniProt ID: | P61289 |
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| Formulation: | Liquid. In PBS pH 7.2 , 1mM DTT |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | A nuclear homo-heptameric form of the 11S proteasome activator built up by 11S subunit γ(designated 11Sγ) was found to facilitate the degradation of an intact proteasome substrate by the 20S proteasome. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependent inter-ring crosstalks: J. Lesne, et al.; Nat. Commun.
11, 6140 (2021),
Abstract;
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