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Proteasome 19S Rpt5/S6a subunit polyclonal antibody

BML-PW8245-0025 25 µl 112.00 USD
BML-PW8245-0100 100 µl 457.00 USD
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Product Details

Alternative Name:26S protease regulatory subunit 6A, Tat-binding protein homolog 1, TBP-1
Immunogen:Recombinant protein corresponding to the N-terminal 100 amino acids of Yta1.
UniProt ID:P33297
GenBank ID:464859
Species reactivity:Yeast
Specificity:Recognizes the Rpt5/S6a subunit of the 19S regulator complex.
Formulation:Liquid. In PBS containing 10mM sodium azide.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Assembly chaperone Nas6 selectively destabilizes 26S proteasomes with defective regulatory particle-core particle interfaces: J.L. Warnock, et al.; J. Biol. Chem. 299, 102894 (2023), Abstract;
Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones: A. Nahar, et al.; Cell Rep. 39, 110918 (2022), Abstract;
Proteasome subunit α1 overexpression preferentially drives canonical proteasome biogenesis and enhances stress tolerance in yeast: L.A. Howell, et al.; Sci. Rep. 9, 12418 (2019), Abstract; Full Text
DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis: A. Nassrallah, et al.; Elife 7, e37892 (2018), Abstract; Full Text
An evolutionarily conserved pathway controls proteasome homeostasis: A. Rousseau, et al.; Nature 536, 184 (2016), Abstract; Full Text
Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation: W.H. Choi, et al.; Nat. Commun. 7, 10963 (2016), Application(s): Western blot, Abstract;
Proteasome Activation is Mediated via a Functional Switch of the Rpt6 C-terminal Tail Following Chaperone-dependent Assembly: V. Sokolova, et al.; Sci. Rep. 5, 14909 (2015), Abstract; Full Text

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