R-enantiomer of rolipram which is more active at inhibition of PDE IV, Ki=06 µM. 10-fold more active than S-rolipram at inhibition of PDE IV. Inhibits antigen-induced contraction of guinea-pig colonic smooth muscle, EC50=0.1 µM.
Product Details
| Alternative Name: | R-(-)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone |
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| Formula: | C16H21NO3 |
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| MW: | 275.4 |
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| CAS: | 85416-75-7 |
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| Purity: | ≥98% (HPLC) |
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| Identity: | Determined by 1H-NMR and MS. |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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