Replaces Prod. #: ALX-480-068
Selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I, IC50=4 µM).
Product Details
| Formula: | C12H18N4O3 |
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| MW: | 266.3 |
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| CAS: | 78033-08-6 |
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| Purity: | ≥98% (TLC) |
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| Identity: | Determined by 1H-NMR and MS. |
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| Appearance: | White solid. |
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| Solubility: | Soluble in 100% ethanol (5mg/ml) or DMSO (5mg/ml) |
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| Shipping: | Ambient |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Use, as supplied, at room temperature for up to 2 years. Store dilutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta: H.S. Ahn et al.; Biochem. Pharmacol.
38, 3331 (1989),
Abstract;
Methylxanthine inhibitors of phosphodiesterases: J.N. Wells & J.R. Miller; Methods Enzymol.
159, 489 (1988),
Abstract;
