Comprising residues 5-23 of the human histone H3 N-terminal tail, this peptide is centered on Lys14, preferred acetylation site for the GCN5/PCAF family of histone acetyltransferases (HATs). May be used as a substrate for assay of PCAF and hGCN5 HATs.
Product Details
| Sequence: | Ac-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-NH2 |
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| MW: | 2068.4 |
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| Formulation: | Lyophilized. |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Lyophilized solid. |
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| Solubility: | Soluble in Water. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases: X.-J. Yang, et al.; Nucleic Acids Res.
32, 959 (2004),
Abstract;
Full Text
Histone acetyltransferases: S.Y. Roth, et al.; Annu. Rev. Biochem.
70, 81 (2001),
Abstract;
Application of a fluorescent histone acetyltransferase assay to probe the substrate specificity of the human p300/CBP-associated factor: R.C. Trievel, et al.; Anal. Biochem.
287, 319 (2000),
Abstract;
