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Histone H3 (human) (5-23) amide

HAT substrate
 
BML-P271-0500 0.5 mg 170.00 USD
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Comprising residues 5-23 of the human histone H3 N-terminal tail, this peptide is centered on Lys14, preferred acetylation site for the GCN5/PCAF family of histone acetyltransferases (HATs). May be used as a substrate for assay of PCAF and hGCN5 HATs.

Product Details

Sequence:Ac-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-NH2
 
MW:2068.4
 
Formulation:Lyophilized.
 
Purity:≥95% (HPLC)
 
Appearance:Lyophilized solid.
 
Solubility:Soluble in Water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 

Product Literature References

The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases: X.-J. Yang, et al.; Nucleic Acids Res. 32, 959 (2004), Abstract; Full Text
Histone acetyltransferases: S.Y. Roth, et al.; Annu. Rev. Biochem. 70, 81 (2001), Abstract;
Application of a fluorescent histone acetyltransferase assay to probe the substrate specificity of the human p300/CBP-associated factor: R.C. Trievel, et al.; Anal. Biochem. 287, 319 (2000), Abstract;

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