Metabolite of triazolam.
Product Details
| Alternative Name: | 8-Chloro-6-(o-chlorophenyl)-4H-s-Triazolo[4,3-a][1,4]-benzodiazepine-1-methanol |
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| Formula: | C17H12Cl2N4O |
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| MW: | 359.2 |
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| CAS: | 37115-45-0 |
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| Purity: | ≥96% (TLC) |
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| Identity: | Determined by 1H-NMR and MS. |
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| Appearance: | White solid. |
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| Solubility: | Soluble in DMSO (5mg/ml warm) or methanol (1mg/ml warm). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole: L. L. von Moltke, et al.; J. Pharmacol. Exp. Ther.
276, 370 (1996),
Abstract;
Immunoassay detection of benzodiazepines and benzodiazepine metabolites in blood: W. Huang & D.E. Moody; J. Anal. Toxicol.
19, 333 (1995),
Abstract;
Triazolam: a review of its pharmacological properties and therapeutic efficacy in patients with insomnia: G. E. Pakes, et al.; Drugs
22, 81 (1981),
Abstract;
Pharmacology of some metabolites of triazolam, alprazolam, and diazepam prepared by a simple, one-step oxidation of benzodiazepines: M. Gall, et al.; J. Med. Chem.
21, 1290 (1978),
Abstract;
