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13(S)-Hydroperoxyoctadeca-9Z,11E-dienoic acid

Inhibits prostacyclin synthase
BML-HP013-0050 50 µg 105.00 USD
BML-HP013-1000 1 mg 1,146.00 USD
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Suppresses activation of platelets. Induces endothelial injury. Constricts isolated coronary arteries. Inhibits prostacyclin synthase.

Product Details

Alternative Name:13(S)-HPODE
Concentration:50µg/ml for 50ug size. 1mg/ml for 1mg size.  
Formulation:Oil dissolved in ethanol.
Shipping:Dry Ice
Long Term Storage:-80°C
Use/Stability:Open ampule and aliquot into suitable tubes or vials. Store at -80°C or colder. For experiments with cells or tissues, aliquots of ethanol solutions may be added directly to aqueous media. For HPLC, aliquots of ethanol solutions should be evaporated to dryness under a stream of nitrogen and HPLC mobile phase added to the desired concentration.  
Regulatory Status:RUO - Research Use Only
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Product Literature References

Rat uterine progesterone receptor analyzed by [3H]R5020 photoaffinity labeling: evidence that the A and B subunits are not equimolar: J. Z. Sun, et al.; Endocrinology 15, 1449 (1987), Abstract;
Experimental myocardial infarction: effects of a lipid peroxide, 13-hydroperoxy linoleic acid on coronary circulation in rats: M. Mizukami, et al.; Arzneimittelforschung 5, 569 (1984), Abstract;
Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes: J. A. Salmon, et al.; Biochim. Biophys. Acta. 523, 250 (1978), Abstract;

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