Cytotoxic product of microsomal lipid peroxidation induced by xenobiotics. Reported to be a specific chemical indicator of lipid peroxidation in rat liver microsomes and in myocardial reperfusion injury. Covalently reacts with LDL and HDL during oxidative modification. Modifies proteins by covalent reaction with histidine and lysine residues. Activates TRPA1.
Product Details
| Formula: | C9H16O2 |
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| MW: | 156.2 |
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| CAS: | 75899-68-2 |
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| Purity: | ≥97% |
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| Appearance: | Colorless oil. |
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| Solubility: | Soluble in 100% ethanol (25mg/ml). |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes: H. Esterbauer, et al.; Free Radic. Biol. Med.
11, 81 (1991),
Abstract;
