Novel inhibitor of ubiquitin C-terminal hydrolase L3 (IC50 = 0.6µM). Displays 125-fold greater selectivity over UCH-L1 (IC50 = 75µM).
Product Details
| Alternative Name: | 4,5,6,7-Tetrachloroindan-1,3-dione |
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| Formula: | C9H2Cl4O2 |
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| MW: | 283.9 |
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| CAS: | 30675-13-9 |
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| Purity: | ≥95% (TLC) |
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| Appearance: | Orange solid. |
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| Solubility: | Soluble in DMSO (25mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Mechanisms, biology and inhibitors of deubiquitinating enzymes: K.R. Love, et al.; Nat. Chem. Biol.
3, 697 (2007),
Abstract;
