Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.
Product Details
| Formula: | C21H16O2 |
| |
| MW: | 300.4 |
| |
| Source: | Synthetic. |
| |
| CAS: | 82389-34-2 |
| |
| Purity: | ≥98% (HPLC) |
| |
| Appearance: | White to off-white solid. |
| |
| Solubility: | Soluble in DMSO (25mg/ml) |
| |
| Shipping: | Ambient |
| |
| Long Term Storage: | -20°C |
| |
| Use/Stability: | Store, as supplied, at -20°C for up to one year. Store solutions at -20°C for up to three months. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
Regiospecific and enantioselective metabolism of 8,9-epoxyeicosatrienoic acid by cyclooxygenase: J.Y. Zhang, et al.; Biochem. Biophys. Res. Commun.
183, 138 (1992),
Abstract;
Selective inhibition and selective induction of multiple microsomal epoxide hydrolases: T.M. Guenther, et al.; Biochem. Pharmacol.
35, 839 (1986),
Abstract;
