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4-Phenylchalcone Oxide

Epoxide hydrolase inhibitor
 
BML-EI108-0020 20 mg 93.00 USD
 
BML-EI108-0100 100 mg 351.00 USD
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Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.

Product Specification

Formula:C21H16O2
 
MW:300.4
 
Source:Synthetic.
 
CAS:82389-34-2
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO (25mg/ml)
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to one year. Store solutions at -20°C for up to three months.
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

Regiospecific and enantioselective metabolism of 8,9-epoxyeicosatrienoic acid by cyclooxygenase: J.Y. Zhang, et al.; Biochem. Biophys. Res. Commun. 183, 138 (1992), Abstract;
Selective inhibition and selective induction of multiple microsomal epoxide hydrolases: T.M. Guenther, et al.; Biochem. Pharmacol. 35, 839 (1986), Abstract;

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