Benzodiazepine inverse agonist. Antagonizes the anxiolytic and anticonvulsant actions of diazepam and reverses the sedative action of flurazepam.
Product Details
Formula: | C12H10N2O |
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MW: | 198.2 |
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CAS: | 65474-79-5 |
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Purity: | ≥98% (HPLC) |
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Appearance: | Yellow solid. |
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Solubility: | Soluble in ethanol or DMSO. |
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Shipping: | Ambient |
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Long Term Storage: | Ambient |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The influence of lipophilic character on receptor binding affinity of a series of beta-carbolines: P. A. Borea, et al.; Biochem. Pharmacol.
37, 3935 (1988),
Abstract;
A benzodiazepine receptor antagonist decreases sleep and reverses the hypnotic actions of flurazepam: W. B. Mendelson, et al.; Science
219, 414 (1983),
Abstract;