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Matrix Metalloproteinase-1 (MMP-1) colorimetric drug discovery kit

BML-AK404-0001 96 wells 624.00 USD
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  • Designed to screen inhibitors of matrix metalloproteinase-1
  • Convenient 96-well plate format
A QUANTIZYME® Assay System. The MMP-1 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-1 (MMP-1, interstitial collagenase, fibroblast collagenase) using a thiopeptide as a chromogenic substrate. The assays are performed in a convenient 96-well plate format. Included are active enzyme, assay buffer, a prototypic control inhibitor (NNGH), and a detailed instruction booklet.

Product Details

Alternative Name:Interstitial collagenase, Fibroblast collagenase
Applications:Colorimetric detection, HTS
Activity assay
Shipping:Dry Ice
Long Term Storage:-80°C
Contents:MMP-1 enzyme (human) (recombinant), substrate, inhibitor, assay buffer, 96-well microplate.
UniProt ID:P03956
Regulatory Status:RUO - Research Use Only

Product Literature References

Anti–elastase, anti–tyrosinase and matrix metalloproteinase–1 inhibitory activity of earthworm extracts as potential new anti–aging agent: N. Azmi, et al.; Asian Pac. J. Trop. Biomed. 4, S348 (2014), Application(s): Evaluate inhibitory effects of earthworms extracts on MMP-1., Abstract; Full Text
Phenolic composition, antioxidant, anti-wrinkles and tyrosinase inhibitory activities of cocoa pod extract: A.A. Karim, et al.; BMC Complement Altern. Med. 14, 381 (2014), Abstract; Full Text
Inhibition of oral pathogens and collagenase activity by seaweed extracts: J.S. Choi, et al.; J. Environ. Biol. 33, 115 (2012), Abstract;
Cleavage site specificity and conformational selection in type I collagen degradation: R. Salsas-Escat, et al.; Biochemistry 49, 4147 (2010), Application(s): Assay with human collagen cells, Abstract;

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