- Designed to screen inhibitors of matrix metalloproteinase-1
- Convenient 96-well plate format
A QUANTIZYME® Assay System. The MMP-1 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-1 (MMP-1, interstitial collagenase, fibroblast collagenase) using a thiopeptide as a chromogenic substrate. The assays are performed in a convenient 96-well plate format. Included are active enzyme, assay buffer, a prototypic control inhibitor (NNGH), and a detailed instruction booklet.
Product Details
| Alternative Name: | Interstitial collagenase, Fibroblast collagenase |
| |
| Applications: | Colorimetric detection, HTS
Activity assay
|
| |
| Shipping: | Shipped on Dry Ice |
| |
| Long Term Storage: | -80°C |
| |
| Contents: | MMP-1 enzyme (human) (recombinant), substrate, inhibitor, assay buffer, 96-well microplate. |
| |
| UniProt ID: | P03956 |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Product Literature References
Anti–elastase, anti–tyrosinase and matrix metalloproteinase–1 inhibitory activity of earthworm extracts as potential new anti–aging agent: N. Azmi, et al.; Asian Pac. J. Trop. Biomed.
4, S348 (2014),
Application(s): Evaluate inhibitory effects of earthworms extracts on MMP-1.,
Abstract;
Full Text
Phenolic composition, antioxidant, anti-wrinkles and tyrosinase inhibitory activities of cocoa pod extract: A.A. Karim, et al.; BMC Complement Altern. Med.
14, 381 (2014),
Abstract;
Full Text
Inhibition of oral pathogens and collagenase activity by seaweed extracts: J.S. Choi, et al.; J. Environ. Biol.
33, 115 (2012),
Abstract;
Cleavage site specificity and conformational selection in type I collagen degradation: R. Salsas-Escat, et al.; Biochemistry
49, 4147 (2010),
Application(s): Assay with human collagen cells,
Abstract;
