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APRIL (human) monoclonal antibody (Aprily-2)

ALX-804-844-C100 100 µg 441.00 USD
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Product Details

Alternative Name:A-Proliferation-inducing ligand, TNFSF 13, CD256
Immunogen:Recombinant human APRIL (aa 93-233).
UniProt ID:O75888
Source:Purified from concentrated hybridoma tissue culture supernatant.
Species reactivity:Human
Applications:IHC (PS)
Recommended Dilutions/Conditions:Immunohistochemistry (paraffin sections (1:500))
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Immunohistochemistry (paraffin sections, 1:500).
Optimal conditions must be determined individually for each application.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
APRIL (human) monoclonal antibody (Aprily-2) Immunohistochemistry
Figure: Biopsy of tumor lesion from a patient with lymphoma (DLBCL) stained with MAb to APRIL (Aprily-2) (ALX-804-844). The biopsy was stained by standard immunohistochemistry. The figure shows the selective accumulation of APRIL around tumor cells.Picture courtesy of Dr. Bertrand Huard (University of Geneva)."
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APRIL (human) monoclonal antibody (Aprily-2) Immunohistochemistry

Product Literature References

Macrophage-mediated chronic lymphocytic leukemia cell survival is independent of APRIL signaling: M.H.A. van Attekum, et al.; Cell Death Discov. 2, 16020 (2016), Application(s): IHC on PPFE, Abstract; Full Text
The source of APRIL up-regulation in human solid tumor lesions: P. Mhawech-Fauceglia, et al.; J. Leukoc. Biol. 80, 697 (2006), Abstract;

General Literature References

BAFF and APRIL: A Tutorial on B Cell Survival: F. Mackay, et al.; Annu. Rev. Immunol. (2002), Abstract;

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