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Breast cancer resistance protein (human) monoclonal antibody (BXP-21)

 
ALX-801-029A-C100 100 µg 650.00 USD
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Replaces Prod. #: ALX-801-029

Product Details

Alternative Name:MXR, BCRP, ABCG2, CD338
 
Clone:BXP-21
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Recombinant human BCRP (breast cancer resistance protein; MXR) (aa 271-396).
 
UniProt ID:Q9UNQ0
 
Species reactivity:Human
 
Specificity:Recognizes an internal epitope of human BCRP.
 
Crossreactivity:Does not cross-react with human P-glycoprotein, MRP1 or MRP2.
 
Applications:ICC, IHC (FS), IHC (PS), WB
 
Recommended Dilutions/Conditions:Immunocytochemistry: Use 1:20-1:50 dilution on acetone fixed cytospin preparations.
Immunohistochemistry (frozen sections): Use 1:20 dilution on acetone fixed frozen sections followed by incubation with rabbit anti-mouse IgG and a monoclonal mouse APAAP complex.
Immunohistochemistry (paraffin sections): Use on formaldehyde-fixed paraffin-embedded human tissues and tumors after pretreatment with 10mM citric acid, pH 6.0, for 20 min.
Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.
 
Application Notes:Immunocytochemistry: cytospin preparations
 
Formulation:Liquid. In PBS containing 0.1% BSA and 0.02% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 

General Literature References

A multidrug resistance transporter from human MCF-7 breast cancer cells: L.A. Doyle, et al.; PNAS 95, 15665 (1998), Abstract; Full Text

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